Statistical Analysis Plan for a multi-centre randomised controlled trial: Early parenteral nutrition vs. standard care in patients not expected to be fed within 24 h of ICU admission.

Doig, Gordon S.; Simpson, Fiona; Heighes,; Sweetman, Elizabeth A.; Heighes, Philippa T.

PDF repository of selected presentations:
Note: If pdfs don't open in Chrome, right click and save to disk or visit this Chrome help page.

US CE accredited webinar:
- Early PN in critical illness Pdf of powerpoint (4 Meg)

Nutrition Workshop at Royal North Shore Hospital 2017:
- Can Early enteral nutrition prevent gut dysfunction Pdf of powerpoint (1.3 Meg)

9th Annual PLA congress on critical care and 3rd military medical university, Daping Hospital ICU, 2017 (Chongqing):
- Early enteral nutrition in the major trauma patient requiring ICU care Pdf of powerpoint (6.2 Meg)

2017 China (Beijing, Nanjing, Chengdu):
- Early enteral nutrition in the ICU: from clinical trials to physiology Pdf of powerpoint (6.2 Meg)

2017 Annual Meeting on Critical Care Medicine and Critical Care Nutrition (Beijing):
- Early enteral nutrition in the ICU: How early is early? Pdf of powerpoint (6.5 Meg)
- How to implement a nutrition guidline: Does knowledge change practice? Pdf of powerpoint (4 Meg)
- How to publish in an English language journal. Pdf of powerpoint (4 Meg)

2017 ASPEN Clinical Nutrition Week, Breakfast Session:
- Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: What the evidence reallys says Pdf of powerpoint (8.8 Meg)

Health economics in ICU nutrition: The time has come! Early EN, European costs (4.7MB pdf)

Excel spreadsheet to support the calculation of local costs of implementing early EN or early PN Excel spreadsheet (82B pdf)

2016 China (local meetings in Zhengzhou, Shanghai, Guangzhou, and Hangzhou ):
- Understanding the benefits of early enteral nutrition in the ICU: From clinical studies to costs: Pdf of powerpoint (4.8 Meg)

2016 Congress of the Chinese Society of Parenteral and Enteral Nutrition (Chengdu):
- Early enteral nutrition in trauma patients requiring intensive care: From clinical studies to costs: Pdf of powerpoint (3.2 Meg)

2016 10th Congress of the Chinese Society of Critical Care Medicine (Zhengzhou):
- How to get your paper published in an English language journal: Pdf of powerpoint (2 Meg)

2015 Chinese Critical Care Congress (Fuzhou, Fujian Province):
- Management of Refeeding Syndrome, An AuSPEN endorsed multi-centre RCT: Pdf of powerpoint (3.3 Meg)

PENSA 2015 (Nagoya, Japan), Taiwan and Manila:
- Economics of early EN: Pdf of powerpoint (8 Meg)

2014 SMACC Gold. Creatinine, much ado about nothing. Powerpoint pdf file (7 Meg pdf)

A narrated talk on nutrition in trauma. Powerpoint ppsx file (20 Meg ppsx)

Nutrition support in the major trauma patient managed with an open abdomen. Open abdomen (6.7MB pdf)

Should we ACCEPT protocolizeed nutrition practice in the ICU? ACCEPT Protocol (9.4MB pdf)

Benchmarking your ICU' feeding performance: How early is early? Global benchmarking project (5.1MB pdf)

Protein dosing in critical illness: New data, new ideas. Protein dosing in the ICU (3MB pdf)

Early nutrition (EN or PN) in critical illness: Clinical evidence, physiology and costs. Early Nutrition (24MB pdf)

Tube feeding diarrhea management protocol of the ACCEPT trial: ACCEPT protocol talk (6.3MB pdf)

Evidence for immunonutrition in sepsis: Sepsis Talk (5.7MB pdf)

[ Back to EBDM Main page ] Any questions or comments please contact gdoig@med.usyd.edu.au
Implemented and designed by John Soer and Gordon Doig
Page last modified on Monday 25 September 2017.

Selected papers and resources:

A short paper on when to use p-values, power and confidence intervals: Users' Guide (128KB)

An Excel tool for estimating 95% Confidence Intervals: Excel tool (21KB)

Excel spreadsheet to support the calculation of local costs of implementing early EN or early PN Excel spreadsheet (82B pdf)

Statistical Analysis Plan for a multi-centre clinical trial: The Early PN Trial (795KB pdf)

Anthropometric Procedures Manual for a multi-centre clinical trial: The Early PN Trial (12.8MB pdf)

Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a full economic analysis of a multicenter randomized controlled trial based on US costs. To download, click here (PMC article)

Modeling mortality in the intensive care unit: comparing the performance of a back-propagation, associative-learning neural network with multivariate logistic regression. To download, click here (PMC article)

Early enteral nutrition in critical illness: a full economic analysis using US costs. To download, click here (PMC article)

Failure to report protocol violations in clinical trials: a threat to internal validity? To download, click here (PMC article)

A systematic review of techniques and interventions for improving adherence to inclusion and exclusion criteria during enrolment into randomised controlled trials. To download, click here (PMC article)

Evidence-based systematic review of the effectiveness of hydrotherapy in acute and chronic medical conditions. To download, click here (136KB pdf)

Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT). To download, click here (PMC article)

Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle. To download, click here (154KB pdf)

NUTRIREA-2 trial finds that early enteral nutrition and early parenteral nutrition do not differ with regards to major clinical outcomes. To download, click here (PMC article)

A review of the true methodological quality of nutritional support trials conducted in the critically ill: Time for improvement. To download, click here (107KB pdf)
- Appendix I : On-line data supplement. To download, click here (165KB pdf)

The relative effectiveness of practice change interventions in overcoming common barriers to change: A survey of 14 hospitals with experience implementing evidence-based guidelines. To download, click here

Browman's practice guidelines development cycle: a conceptual tool for practice guidelines development and implementation. To download, click here

Efficient literature searching: a core skill for the practice of evidence-based medicine. To download, click here (298KB pdf)

Randomization and allocation concealment: A practical guide for researchers. To download, click here (98KB pdf)

Health care costs, long-term survival, and quality of life following intensive care unit admission after cardiac arrest. To download, click here (PMC article)

Evidence-based veterinary medicine: What it is, what it isn't and how to do it. To download, click here (41KB pdf)

Clinical and electrophysiologic associations with outcome in initially comatose survivors of cardiac arrest. To download, click here (PMC article)

Surgical case costing: is trauma underfunded according to resource intensity weights. To download, click here

The Southwestern Ontario joint replacement pilot project: elecytronic point-of-care data collection. To download, click here (PMC article)

Itracranial pressure monitoring and outcomes after traumatic brain injury. To download, click here (PMC article)

World Health Organization Consultation meeting on traditional and modern medicine: Harmonizing the two approaches. To download, click here (290KB pdf)

Severity of illness scoring in the ICU: A comparison of logistic regression and artificial neural networks. To download, click here (894KB pdf)

[ Back to EBDM Main page ] Any questions or comments please contact gdoig@med.usyd.edu.au
Implemented and designed by John Soer and Gordon Doig
Page last modified on Monday 25 September 2017.

YouTube repository of selected presentations (Evidencebased.net Channel):
To view in full screen: Start video then click on YouTube link in lower right corner of video.

[ Back to EBDM Main page ] Any questions or comments please contact gdoig@med.usyd.edu.au
Implemented and designed by John Soer and Gordon Doig
Page last modified on Monday 25 September 2017.

YouTube Live Seminars(Evidencebased.net Channel):

[ Back to EBDM Main page ] Any questions or comments please contact gdoig@med.usyd.edu.au
Implemented and designed by John Soer and Gordon Doig
Page last modified on Monday 25 September 2017.

Evidence-based guidelines for nutritional support of the critically ill: Results of a bi-national guideline development conference.
Note: If pdfs don't open in Chrome, right click and save to disk or visit this Chrome help page.

To download, click here (282 pages, Version 7, 1 Sept 2005, 2.9 Meg pdf)
- Guideline implementation strategy. Pdf of ppt presentation. To download, click here (1.2 Meg pdf)
- Full colour, 2-page, high resolution A4 (letter) sized version of guideline. Evidence-based guidelines for nutritional support of the critically ill: Results of a bi-national guideline development conference. To download, click here (247KB pdf)
- Full colour, high resolution A3 (poster) sized version of guideline. Evidence-based guidelines for nutritional support of the critically ill: Results of a bi-national guideline development conference. To download, click here (417KB pdf)

[ Back to EBDM Main page ] Any questions or comments please contact gdoig@med.usyd.edu.au
Implemented and designed by John Soer and Gordon Doig
Page last modified on Monday 25 September 2017.